اثر هشت هفته تمرین هوازی بر پروتئین واکنش‌دهندۀ C و نیمرخ چربی مردان مبتلا به سرطان کولورکتال

نوع مقاله: مقاله پژوهشی

نویسندگان

1 کارشناس ارشد، فیزیولوژی ورزش، دانشکده علوم ورزشی،‌دانشگاه ازاد اسلامی، واحد شیراز

2 استادیار گروه علوم ورزشی، پردیس بین‌الملل کیش، دانشگاه تهران، جزیرۀ کیش، ایران

3 دانشیار گروه علوم ورزشی، دانشکده تربیت بدنی و علوم ورزشی، دانشگاه آزاد اسلامی واحد شیراز، فارس، ایران

4 کارشناس ارشد فیزیولوژی ورزش، دانشکده تربیت بدنی و علوم ورزشی دانشگاه آزاد اسلامی واحد شیراز، فارس، ایران

چکیده

 
هدف اصلی این پژوهش بررسی اثر 8 هفته تمرین هوازی بر پروتئین واکنش‌دهندۀ C و نیمرخ چربی مردان مبتلا به سرطان کولورکتال بود. بدین‌منظور، 27 مرد مبتلا به سرطان کولورکتال، با میانگین سن 28/11± 56/51 سال، قد 07/0± 71/1متر، وزن 03/12±69/69 کیلوگرم و شاخص تودۀ بدنی 67/3±67/23 کیلوگرم بر متر مربع، به‌عنوان آزمودنی انتخاب شدند. آزمودنی‌ها به دو گروه آزمایش (15 نفر) و کنترل (12 نفر) تقسیم شدند. در ابتدای پژوهش از آنان درخواست شد تا پرسشنامۀ آمادگی شرکت در فعالیت بدنی (PAR-Q) را کامل کنند. برنامۀ فعالیت ورزشی شامل 8 هفته تمرین هوازی 3 جلسه در هفته به مدت 45 دقیقه و با شدت 60-50 درصد ضربان قلب هدف انجام گرفت. برای توصیف داده‌ها مانند میانگین و انحراف معیار از آمار توصیفی و برای تحلیل آماری داده‌ها، از آزمون تحلیل کوواریانس استفاده شد (05/0 α≤). نتایج نشان داد، 8 هفته تمرین هوازی بر میزان CRP (251/99F= و000/0P=)، BMI (25/11F= و02/0P=)، کلسترول (95/6F= و 015/0P=) و VO2peak (56/16F= و 02/0 P=) اثر معنادار دارد. اما بر LDL،HDL و TG اثر معنادار نداشت (05/0P≤). در کل، 8 هفته فعالیت ورزشی هوازی با شدت متوسط می‌تواند CRP و کلسترول را در مردان مبتلا به سرطان کولورکتال کاهش و VO2peak را در این افراد افزایش دهد.

کلیدواژه‌ها


عنوان مقاله [English]

The Effect of 8 Weeks of Aerobic Exercise on c-Reactive Protein and Lipid Profile in Men with Colorectal Cancer

نویسندگان [English]

  • tayebeh Tadayon 1
  • Reza Nouri 2
  • Mehrzad Moghadasi 3
  • Hoda Darvishi 4
1 M.S in Exercise Physiology, Faculty of Sport Science, Islamic Azad University, Shiraz Branch, Shiraz, Iran
2 Assistant Professor, Department of Sport Sciences, Kish International Campus, University of Tehran, Kish, Iran
3 Associate Professor in Exercise Physiology, Faculty of Sport Science, Islamic Azad University, Shiraz Branch, Shiraz, Iran
4 M.S in Exercise Physiology, Faculty of Sport Science, Islamic Azad University, Shiraz Branch, Shiraz, Iran
چکیده [English]

 
The main aim of this study was to investigate the effect of 8 weeks of aerobic exercise on C-reactive protein and lipid profile in men with colorectal cancer.27 male patients with colorectal cancer (mean age 51.56±11.28 years, height 1.71±0.07 m, weight 69.69±12.03 kg and body mass index 23.67±3.67 kg.m-2) were selected as the subjects. Subjects were divided into two groups: experimental (n=15) and control (n=12). At the beginning of the study, they were asked to complete Physical Activity Readiness Questionnaire (PAR-Q). The exercise program included 8 weeks of aerobic exercise, 3 sessions per week, 45 minutes per session and was performed with an intensity of 50-60% of target heart rate. Descriptive statistics were used to describe data such as mean and standard deviation and analysis of covariance was used to statistically analyze the data (α≤0.05). The results showed that 8 weeks of aerobic exercise had a significant effect on CRP (F=99.251 and P=0.000), BMI (F=11.25 and P=0.02), cholesterol (F=6.95 and P=0.015) and VO2peak (F=16.56, P=0.02). However, aerobic exercise had no significant effect on LDL, HDL and TG (P≥0.05). In conclusion, 8 weeks of aerobic exercise with moderate intensity can reduce CRP and cholesterol and increase VO2peak in men with colorectal cancer.

کلیدواژه‌ها [English]

  • colorectal cancer
  • Inflammatory Markers
  • cardiovascular risk factors
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