اثر مصرف حاد عصارۀ جینکوبیلوبا بر شاخص‌های کوفتگی عضلانی و پروتئین واکنشگر-سی (CRP) متعاقب فعالیت تناوبی شدید (HIIT) در دختران فعال

نوع مقاله : مقاله پژوهشی

نویسندگان

1 دانشیار فیزیولوژی ورزشی، واحد مهاباد، دانشگاه آزاد اسلامی، مهاباد، ایران

2 استادیار فیزیولوژی ورزشی، واحد بناب، دانشگاه آزاد اسلامی، بناب، ایران

3 استادیار فیزیولوژی ورزشی، دانشگاه پیام نور، مرکز بناب، ایران

چکیده

 نتایج پژوهش‌ها بیانگر این است که فعالیت‌های ورزشی شدید به افزایش شاخص‌های التهابی، آسیب عضلانی و همچنین کاهش عملکرد در ورزشکاران منجر می‌شوند. با این حال، بیان شده است که مداخلات تغذیه‌ای ممکن است التهاب و آسیب سلولی عضلانی را کاهش دهد. ازاین‌رو هدف از تحقیق حاضر بررسی اثر مصرف حاد عصارۀ جینکوبیلوبا بر غلظت کراتین کیناز (CK) و لاکتات دهیدروزناز (LDH)، به‌عنوان شاخص‌های کوفتگی عضلانی و پروتئین واکنشگر-سی (CRP) متعاقب فعالیت تناوبی شدید (HIIT) در دختران فعال (سن 43/3±06/24 سال، وزن 03/6±56/57 کیلوگرم، قد 87/4±98/159 سانتی‌متر و شاخص تودۀ بدن 41/2±51/22) بود. در یک مطالعۀ نیمه­تجربی 24 دختر فعال به‌صورت هدفمند و در دسترس انتخاب شدند و تصادفی در دو گروه مکمل جینکوبیلوبا و شبه‌دارو قرار گرفتند. افرادی که در گروه مکمل قرار گرفتند، روزانه 160 میلی‌گرم مکمل عصارۀ جینکوبیلوبا را به مدت 3 هفته دریافت کردند، درحالی‌که در گروه شبه‌دارو نیز شبه‌دارو (دکستروز طعم داده‌شده) به همین شکل تجویز شد. همۀ آزمودنی‌ها پس از 3 هفته مکمل یاری فعالیت تناوبی شدید RAST (شامل دو دوره آزمون 6 وهله دوی سریع با حداکثر شدت در مسافت 35 متری با وهله‌های بازیافتی 10ثانیه بین هر تکرار) را انجام دادند. نمونه‌های خون وریدی کلیه آزمودنی‌هاآزمودنی‌ها در چهار مرحله جهت اندازه‌گیری شاخص‌های CK، LDH و CRP جمع‌آوری شد. نتایج نشان داد که فعالیت HIIT موجب افزایش معنا‌دار سطوح CK، LDH و CRP در مراحل بلافاصله و 24 ساعت پس از فعالیت ورزشی در هر دو گروه دارونما و مکمل می‌شود (05/0‌>P). با این حال، مصرف مکمل جینکوبیلوبا موجب کاهش معنا‌دار سطوح نشانگرهای  CKو CRP متعاقب فعالیت HIIT در مقایسه با گروه شبه‌دارو شد (05/0‌>P). نتایج پژوهش حاضر بیانگر این بود که مصرف مکمل عصارۀ جینکوبیلوبا می‌تواند در جلوگیری از افزایش نامطلوب شاخص‌های کوفتگی عضلانی و التهابی متعاقب فعالیت‌های شدید ورزشی در دختران فعال مؤثر باشد. 

کلیدواژه‌ها


عنوان مقاله [English]

The Acute Effect of Ginkgo Biloba Extract on Muscle Soreness Markers and C-reactive Protein (CRP) After High Intensity Interval Training (HIIT) in Active Girls

نویسندگان [English]

  • Sirvan Atashak 1
  • Reza Roshdi Bonab 2
  • Vahideh Kianmarz Bonab 3
1 Associate professor of Exercise Physiology, Mahabad Branch, Islamic Azad University, Mahabad, Iran
2 Assistant professor of Exercise Physiology, Bonab Branch, Islamic Azad University, Bonab, Iran
3 Assistant professor of Exercise Physiology, Payame Noor University, Bonab, Iran
چکیده [English]

 
The results of the studies indicated that strenuous acute exercise can lead to increased inflammatory indices, muscle injury and decreased performance in athletes. Nevertheless, it has been suggested that the nutritional intervention may diminish inflammation and muscle cell damage. Hence, the aim of this investigation was to study the acute effect of ginkgo biloba extract on creatine kinase (CK) and lactate dehydrogenase (LDH) levels, as muscle soreness markers, and C- reactive protein (CRP) after high intensity interval training (HIIT) in active girls. In a quasi-experimental study 24 active girls (mean age: 24.06±3.43 years; weight: 57.56±6.03 kg; height: 159.98±4.87 cm and body mass index: 22.51±2.41 kg/m2) randomly assigned into two Ginkgo biloba supplement and placebo groups. Subjects in supplement group consume 160 mg/day of ginkgo biloba extract daily for 3 weeks while the placebo group received the same amount of placebo. All subjects of both groups underwent in high intensity interval exercise RAST (including two sets of 6 repetitions of two fast running 35 meters and with a maximum intensity performed after the rest interval of 10 seconds in each repetition) after 3weeks of supplementation. Venous blood samples were collected for assessment of CK, LDH and CRP indices at four stages. Data was analyzed by repeated measure ANOVA and Bonferroni post-hoc test at α ≤ 0.05. The results showed that the HIIT increased the levels of CK, LDH and CRP at the immediately and 24 hours after exercise in both placebo and supplement groups (p<0/05). Nevertheless, ginkgo biloba supplementation attenuated their increase of CK and CRP indicators following high intensity exercise compared to control groups (p<0/05). The results of this study indicated that ginkgo biloba supplementation can be effective in alleviates the inflammation and muscular damage by the HIIT in active girls.

کلیدواژه‌ها [English]

  • Creatine kinase
  • C-reactive protein
  • Ginkgo biloba exetact
  • High intensity interval exercise
  • lactate dehydrogenase
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