اثر هشت هفته تمرین هوازی بر سطوح سرمی FGF21 ، آپولیپوپروتئین A-1 و نسبت LDL-C به HDL-C در زنان چاقd

نویسندگان

1 استادیار گروه فیزیولوژی ورزشی، واحد آیت الله آملی، دانشگاه آزاد اسلامی، آمل، ایران

2 کارشناس ارشد گروه فیزیولوژی ورزشی، واحد آیت الله آملی، دانشگاه آزاد اسلامی، آمل، ایران

3 استادیار گروه فیزیولوژی ورزشی، واحد ساری، دانشگاه آزاد اسلامی، ساری، ایران

چکیده

هدف از پژوهش حاضر اثر هشت هفته تمرین هوازی بر سطوح سرمی FGF21، آپولیپوپروتئین A-1 و نسبت LDL-C به HDL-C در زنان چاق بود. به­همین منظور 20 زن چاق (سن97/1±25/30 سال، قد 06/0±61/1 متر، وزن 67/6±29/85 کیلوگرم، شاخص توده بدنی 91/1±72/32 کیلوگرم بر متر مربع به طور تصادفی به 2 گروه تمرین هوازی و کنترل تقسیم شدند. آزمودنی ها در گروه تجربی فعالیت هوازی را با شدت 60-75 درصد ضربان قلب هدف به مدت  8 هفته، هفته ای سه روز و زمان 30 تا 45 دقیقه انجام دادند. آزمون آنالیز واریانس در اندازه گیری مکرر جهت تجزیه و تحلیل داده ها مورد استفاده قرار گرفت. تفاوت معنادار در سطح 05/0> p پذیرفته شد. نتایج تحقیق نشان داد که سطوح سرمی FGF21 در گروه تمرین در دوره 8 هفته بعد از فعالیت افزایش معناداری یافته است
(008/0 = P) ، اما این افزایش در مقایسه با گروه کنترل معنادار نبود. همچنین سطوح سرمی APO A-1 در گروه تمرین در دوره 8 هفته بعد از فعالیت افزایش معناداری یافته است (021/0 = P) ، اما این افزایش در مقایسه با گروه کنترل معنادار نبود. نسبت LDL-C به HDL-C در دوره 8 هفته بعد از فعالیت هوازی کاهش معنادارییافت (011/0 = P). با توجه به نتایج بالا این احتمال وجود دارد که تمرینات هوازی بتواند از طریق افزایش احتمالی FGF21و همچنین کاهش نسبت LDL-C به HDL-C در جلوگیری از بسیاری از بیماریهای مرتبط با چاقی سودمند باشد. 

کلیدواژه‌ها


عنوان مقاله [English]

The Effect of 8 Weeks of Aerobic Exercise on Serum Levels of FGF21, Apolipoprotein A-1 and LDL-C to HDL-C Ratio in Obese Women

نویسندگان [English]

  • Asieh Abbassi Daloii 1
  • Somayeh Hedayatzadeh 2
  • Ahmad Abdi 1
  • Hajar Abbaszadeh Sourati 3
1 Assistant Professor, Department of Exercise Physiology, Ayatollah Amoli Branch, Islamic Azad University, Amol, Iran
2 MSc, Department of Exercise Physiology, Ayatollah Amoli Branch, Islamic Azad University, Amol, Iran
3 Assistant Professor, Department of Exercise Physiology, Sari Branch, Islamic Azad University, Sari, Iran
چکیده [English]

The aim of the present study was the effect of 8 weeks of aerobic exercise on serum levels of FGF21, Apolipoprotein A-1 and LDL-C to HDL-C ratio in obese women. 20 obese women (age 30.25 ± 1.97 yr, height 1.61 ± 0.06 m, weight 85.29 ± 6.67 kg, BMI 32.72 ± 1.91 kg/m2) were randomly divided into 2 groups: aerobic exercise and control. Subjects in the experimental group performed aerobic exercise at intensity of 60-75% target heart rate for 8 weeks, 3 days per week for 30-45 minutes. Analysis of variance with repeated measures was used to analyze the data. Significant difference at P˂0.05 was accepted. The results showed that serum levels of FGF21 in the exercise group significantly increased (P=0.008) after 8 weeks of exercise but this increase was not significant compared to the control group. Also, serum levels of APO A-1 significantly increased (P=0.021) in the exercise group after 8 weeks of exercise but this increase was not significant compared to the control group. The ratio of LDL-C to HDL-C significantly reduced (P=0.011) after 8 weeks of aerobic exercise. It is possible that aerobic exercise can help prevent many diseases associated with obesity through a probable increase in FGF21 as well as a reduction in LDL-C to HDL-C ratio.
 

کلیدواژه‌ها [English]

  • Aerobic exercise
  • APO A-1
  • LDL-C
  • HDL-C
  • obese women
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