عنوان مقاله [English]
The aim of the present study was to investigate the effect of endurance-resistance training on serum changes of homocysteine, interleukin-6, and IL-10 in men with heart disease. For this purpose, 38 patients who referred to medical cardiovascular centers of Shahin Shahr city were selected by convenience sampling method. The patients had undergone bypass surgery or angioplasty balloon. Patients filled out a demographic questionnaire and necessary tests were conducted to determine their risk factors. Before and after the training, anthropometric indexes (weight, waist circumference, hip circumference and subcutaneous fat in three regions) were measured and blood tests for IL-6, IL-10, homocysteine and walk test for 6 min. (to determine physical capacity) were carried out. The training protocol lasted 24 sessions, 3 days a week, one hour each session. Results showed that the rehabilitation program significantly reduced homocysteine and inflammatory cytokines. Overall, the present study showed that a rehabilitation program with concurrent resistance-endurance training can be a suitable method to improve functional capacity in patients with heart disease given the specific effect of each type of training.
.رستمی س، فرامرزی م، ارباب گ. (1393) تاثیر دو شیوه تمرینی بر غلظت سرمی سایتوکین های التهابی بازیکنان نوجوان فوتبال. نشریه دانشگاه علوم پزشکی هرمزگان، شماره13، 87-96.
2.Adams J, Cline MJ, Hubbard M, McCullough T, Hartman J. (2006) A newparadigm for post–cardiac event resistance exercise guidelines.AM J Cardiol. 97(2): 281–286.
3.Anderson JL, Muhlestein JB, Horne BD, et al. (2000). Plasma homocysteinepredicts mortality independently of traditional risk factors and Creactive protein in patients with angiographically defined coronaryartery disease. Circulation; 102(11): 1227-1232.
4.Bots ML, Launer LJ, Lindemans J, et al.(1997). Homocysteine,atherosclerosis and prevalent cardiovascular disease in the elderly:The Rotterdam Study. J Intern Med; 242(4): 339-347.
5.Burtis CA, Ashwood ER, Brouns DE. (2006). Clinical chemistry and molecular diagnostics. 4th ed. USA: Elsevier; 118-121.
6.Choo J, Burke LE, Hong K.P. (2007). Improved quality of life with cardiacrehabilitation for post–myocardial infarction patients in Korea. European Journal of Cardiovascular Nursing; 6 (3): 166–177.
7.Christen WG, Ajani UA, Glynn RJ, Hennekens CH. (2006).Blood levels of homocysteine and increased risks ofcardiovascular disease: causal or casual. Arch Intern Med.: 160(4): 422-434.
8.Danesh J, Lewington S.(2009). Plasma homocysteine and coronary heart disease: systematic review of publishedepidemiological studies. J Cardiovasc Risk.; 5(4): 229-232.
9.Erfurt JC, Holtyn K.(1991). Health promotion in small business what worksand what doesn’t work. J Occup Med; 33:66–73.
10.Fernandez – Real JM, Vayreda M, Richard C, Gutierrez C, Broch M, vendrell J, Ricart W. (2001). "Circulating interleukin 6 levels, blood pressure and insulin sensitivity in apparently healthy men and women". J Clin endocrinol Metab. 86: PP:1154-1159.
11. Ford ES, Smith SJ, Stroup DF, Steinberg KK, Mueller PW, Thacker SB. (2002). Homocyst(e)ine and cardiovasculardisease: a systematic review of the evidence with special emphasis on case-control studies and nested case-controlstudies. Int J Epidemiol; 31(1): 59-70.
12. Franklin BA, Kahn JK, Gordon NF, Bonow R.O. (2004) A cardioprotective“polypill”? Independent and additive benefits of lifestyle modification. The American Journal of Cardiology; 94(2):162–166.
13.Freimark D, Shechter M, Schwamenthal E, Tanne D, Elmaleh E, Shemesh Y, et al. (2007). Improved exercise tolerance and cardiac function insevere chronic heart failure patients undergoing a supervised exerciseprogram. Int. J. Cardiol; 116(3, 4): 309–314.
14.Gayda M, Brun C, Juneau M, Levesque S, Nigam A. (2008). Long–termcardiac rehabilitation and exercise training programs improve metabolicparameters in metabolic syndrome patients with and without coronaryheart disease. Nutrition, Metabolism and Cardiovascular disease; 18(2): 142–151.
15. George NW, Joseph L. (1998). Homocystein and Atherothrombosis. New Engl J Med; 338(15): 1042-1050.
16. Glowacki SP, Martin SE, Maurer A, Baek W, et al. (2004). Effects ofresistance, endurance, and concurrent exercise on training outcomes inmen. Med Sci Sports Exerc; 36 (12): 2119–27.
17. Heyward Vivian H. (1998). Advance fitness assessment and exerciseprescription. 3rd Edition. The Cooper Institute for Aerobics Research. DallasTX: Advance Fitness Assessment & Exercise Prescription. P: 48.
18. Jankowska EA, Wegrzynowska K, Superlak M, Nowakowska K, Lazorczyk M, Biel B, et al. (2007)The 12–week progressive quadricepsresistance training improves muscle strength, exercise capacity andquality of life in patients with stable chronic heart failure. International Journal of Cardiology. 89: 114-120.
19. Karapolat H, Eyigör S, Zoghi M, Yagd T, Nalbangil S, Durmaz B.(2007). Comparison of hospital–supervised exercise versus home–based exercisein patients after orthotopic heart transplantation: effects on functionalcapacity, quality of life, and psychological symptoms. Transplantation Proceedings; 39 (5): 1586–1588.
20. Kida K, Osada N, Akashi YJ, Sekizuka H, Omiya K, Miyake F. (2008). Theexercise training effects of skeletal muscle strength and muscle volumeto improve functional capacity in patients with myocardial infarction. International Journal of Cardiology.14; 28-37.
21.Kumaran K, Fall CHD, Martyn CN, Vijayakumar M, Stein C, Shier R. (2008). Left ventricular mass and arterial compliance: relation to coronary heart disease and its risk factors in South Indian adults. International Journal of Cardiology; 83(1):1–9.
22. Lavie CJ, Morshedi–Meibodi A, Milani R.V. (2008). Impact of cardiacrehabilitation on coronary risk factors, inflammation, and the metabolic syndrome in obese coronary patients. J Cardiometab Syndr; 3 (3):136–140.
23. Leon AS, Franklin BA, Costa F, Balady GJ, Berra KA, Stewart KJ, et al. (2005). Cardiac rehabilitation and secondary prevention of coronary heartdisease. Circulation; 111:369–376.
24.MacMillan JS, Davis LL, Durham CF, Matteson E.S. (2006). Exercise andheart rate recovery. Heart & Lung: The Journal of Acute and Critical Care; 35 (6): 383–390.
25. Pashkow FJ, Dafce WA. (1999). Clinical cardiac rehabilitation 2nd edition, Baltimore: Wiliams and Wikins: 458-66.
26. Pezeshkiyan M, Norri M, Refahi R, Afrasiabi A, Rahbani M, Qujeq D. (2005). Relationship between hyperhomocysteinemiaand oxidative stress with severity of atherosclerotic lesion. J Med Sci; 5(4): 243-246.
27.Ritchie Gemma M, Keech AC, ASPAC Collaborative Group.(2001) Asia–pacific collaboration on coronary heart disease risk factor intervention:Study design and methods. Heart, Lung and Circulation; 10 (1): 24–29.
28. Schmidt WD, Biwer CJ, Kalscheuer L.K. (2001). Effects of long versusshort bout exercise on fitness and weight loss in overweight females. Journal of the American College of Nutrition; 20 (5): 494–501.
29. Selhub J, Jacques PF, Rosenberg IH, Rogers G, Bowman BA, Gunter EW, et al.(1999). Serum total homocysteineconcentrations in the third National Health and Nutrition Examination Survey (1991-1994): population reference rangesand contribution of vitamin status to high serum concentrations. Ann Intern Med; 131(5): 331-339.
30. Shi L. (1992). The impact of increasing intensity of health promotionintervention on risk reduction. Eval Health Prof; 15(1):3–25.
31.Sykes K, Choo LL, Cotterrell M. (2004). Accumulating aerobic exercisefor effective weight control. J R Soc Health; 124 (1) :24–8.
32.Smith Jk, Dykes R, Douglas JE, Krishnaswamy G, Bork S.(2007). "Long term exercise and atherogenic activity of blood mononuclear cells in persons at risk of developing ischemic heart disease". JAMA. 281: PP:1722-1727.
33. Taylor RS, Brown A, Ebrahim S, Jolliffe J, Noorani H, et al. (2004). Exercise–based rehabilitation for patients with coronary heart disease: systematicreview and meta–analysis of randomized controlled trials, Am J Med; 116 (10): 682–692.
34. Thompson PD, Franklin BA, Balady GJ, Blair SN, Corrado D, Estes M, et al. (2007). Exercise and Acute cardiovascular events. AHA; ACSM.
35.Ueland PM, Refsum H, Beresford SA, Vollset SE. (2010). The controversy over homocysteine and cardiovascular risk. Am J Clin Nutr; 72(2): 324-332.
36. Wannamethee SG, Lowe GD, Whincup PH, Rumley A, Walker M, Lennon L., (2002). "Physical activity and hemostatic and inflammatory variables in elderly men". Circulation. 105: PP:1785-1790.