پاسخ شاخص های التهابی بزاقی مردان با سنین مختلف متعاقب فعالیت ورزشی وامانده ساز با کارسنج دستی و پایی

نویسندگان

1 دانشجوی کارشناسی ارشد، گروه فیزیولوژی ورزش، دانشگاه آزاد واحد ساری، ساری، ایران

2 استاد گروه فیزیولوژی ورزشی، دانشکدة تربیت بدنی، دانشگاه مازندران ، مازندران ، ایران

چکیده

هدف پژوهش حاضر مقایسه پاسخ برخی شاخص­های التهابی بزاقی شامل اینترفرون گاما(INF-g) و اینترلوکین- 6 (IL-6)مردان با سنین مختلف متعاقب فعالیت ورزشی وامانده ساز با کارسنج دستی و پایی بود. 36 مرد سالم در سه رده سنی کودکان(7/1±7/12 سال)، میانسال(9/4±3/34 سال) و سالمند(1/2±55 سال) دو نوع پروتکل کارسنج پایی و دستی را تا حد واماندگی اجرا کردند. شدت اولیه برای کارسنج پایی حدود 50 وات و برای کارسنج دستی 25 وات بود و هر 2 دقیقه 25 وات به هر دو پروتکل افزوده گردید. شاخص های بزاقی قبل و بلافاصله پس از اجرای هر دو پروتکل اندازه گیری شد. داده ها با t وابسته، آنالیز واریانس یکراهه وآزمون تعقیبی توکی تحلیل شد. هر دو پروتکل باعث افزایش معنادار مقادیر IL-6 و IFN-g در هر سه گروه شد، اما تفاوت معنی داری در مقادیر این شاخص ها در ورزش دست و پا بین گروه ها مشاهده نشد. به هنگام مقایسه گروه ها در ورزش دست، مقادیر IFN-g در گروه میانسال و سالمند افزایش بیشتری نسبت به گروه کودکان نشان داد، اما در مقادیر IL-6 تفاوت معناداری بین گروه ها وجود نداشت. همچنین مقایسه گروه ها در ورزش پا، تفاوت معناداری در مقادیر IFN-g و IL-6 را نشان نداد. با توجه به این نتایج می توان گفت که افزایش سایتوکین های بزاقی IL-6 و IFN-g بدنبال فعالیت بدنی وامانده ساز بویژه در گروه سنی سالمندان و کودکان، ممکن است یک مکانیسم دفاعی در برابر استرس ناشی از ورزش باشد.

کلیدواژه‌ها


عنوان مقاله [English]

The Response of Salivary Inflammatory Markers in Men with Different Ages Following Exhaustive Exercise with Arm and Leg Ergometer

نویسندگان [English]

  • Fatemeh Nikzad 1
  • Valiollah Dabidi Roshan 2
1 MSc Student of Exercise Physiology, Islamic Azad University, Sari Branch, Sari, Iran
2 Professor, Department of Exercise Physiology, Faculty of Physical Education, Mazandaran University, Mazandaran, Iran
چکیده [English]

The aim of this study was to compare the response of some salivary inflammatory markers including interferon gamma (IFN-g) and interleukin-6 (IL-6) in men with different ages following an exhaustive exercise with hand and leg ergometer. 36 healthy men in three age groups of children (12.7± 1.7 yr), middle-aged (34.3± 4.9 yr) and elderly (55±2.1 yr) performed two types of leg and arm ergometer protocols to exhaustion. Initial intensity of leg ergometer was 50 watt and arm ergometer was 25 watt. 25 watts were added to both protocols every 2 minutes. Salivary markers were measured before and immediately after both protocols.  The data were analyzed by dependent t test, one-way analysis of variance and Tukey post hoc test. Both protocols significantly increased the values of the IFN-g and IL-6 in all three groups, but no significant differences were observed in the values of these markers in arm and leg exercises among the groups. When groups were compared in arm exercises, the amounts of IFN-g in middle-aged and elderly groups showed a greater increase than children group, but there was no significant difference in values of IL-6 among the groups. Also, while comparing the groups in the leg exercises, no significant differences were observed in levels of IFN-g and IL-6. Given these results, it can be noted that increased salivary cytokines of IL-6 and IFN-g following exhaustive exercise, particularly in the elderly and children groups, may be a defensive mechanism against exercise-induced stress.

کلیدواژه‌ها [English]

  • non-invasive
  • Saliva
  • aging
  • exhaustive exercise
  • Inflammation

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