مقایسه تاثیر ورزش‌های صبحگاهی و عصرگاهی، بر غلظت ایمونوگلوبین A،کورتیزول و پروتئین‌های تام بزاقی در مردان میانسال

نویسندگان

1 دانشیار فیزیولوژی ورزشی، دانشکده علوم ورزشی، دانشگاه بوعلی سینا، همدان، ایران

2 کارشناس ارشد فیزیولوژی ورزش، دانشکده علوم ورزشی، دانشگاه بوعلی سینا، همدان، ایران

3 دانشجوی دکترای فیزیولوژی ورزش، دپارتمان فیزیولوژی ورزشی، پژوهشکده طب ورزشی، پژوهشگاه تربیت بدنی و علوم ورزشی، تهران، ایران

چکیده

این پژوهش به منظور مقایسه‌ی برنامه‌های ورزشی صبحگاهی و عصرگاهی بر روی تغییرات سطوح ایمنوگلوبین آ (IgA)، کورتیزول و پروتئین تام بزاقی مردان میانسال طراحی گردیده بود. بدین منظور، 12 مرد میانسال (سن 87/6±42/53 سال؛ نمایه‌ی توده‌ی بدنی 88/2±21/25 کیلوگرم در هر متر مربع) در این بررسی، مورد پژوهش قرار گرفتند. آزمودنی ها در یک جلسه برنامه‌ی ورزشی استقامتی به مدت 45 دقیقه، با شدت 65 درصد ضربان قلب بیشینه، در صبح (بین ساعات 7 تا 8 صبح) و عصر (بین ساعات 5 تا 6 عصر) به فاصله دو روز از هم شرکت کردند. سطوح بزاقی ایمنوگلوبین­آ، کورتیزول و پروتئین تام بزاقی در صبح و عصر (پیش از ورزش و پس از ورزش) با استفاده از روش الایزا مورد سنجش قرار گرفت. پس از پایان پژوهش داده‌ها با استفاده از آنالیز واریانس اندازه‌های تکراری و آزمون تعقیبی بونفرونی مورد آزمون قرار گرفتند. یافته‌های این پژوهش نشان داد که برنامه‌های ورزشی صبحگاهی به‌صورت معناداری سطوح غلظتی کورتیزول بزاق را کاهش داده‌اند (03/0=P). هیچ تغییر معنادار دیگری بین دیگر ارزیابی‌ها مشاهده نگردید. در نتیجه، برنامه‌های ورزشی صبحگاهی سطوح بزاقی کورتیزول بزاق را در مردان میانسال کاهش می‌دهد.

کلیدواژه‌ها


عنوان مقاله [English]

A Comparison of the Effect of Morning and Evening Exercises on Salivary Immunoglobulin A, Cortisol, and Total Proteins in Middle-Aged Men

نویسندگان [English]

  • Mohammad Ali Samavati Sharif 1
  • Jalal Ghasemi 2
  • Hojjatollah Siavoshy 3
1 Associate Professor in Exercise Physiology, Faculty of Sport Sciences, University of Bu Ali Sina, Hamedan, Iran
2 MSc of Exercise Physiology, Faculty of Sports Sciences, Bu Ali Sina University, Hamedan, Iran
3 PhD Student in Exercise Physiology, Department of Exercise Physiology, Sports Medicine Research Center, Sport Sciences Research Institute, Tehran, Iran
چکیده [English]

This study was designed to compare morning and evening exercises on a change in levels of salivary immunoglobulin A (IgA), cortisol, and total protein in middle-aged men. For this purpose, 12 middle-aged men (age: 53.42±6.87 years; BMI: 25.21±2.88 kg/m2) participated in this study. They had an endurance training session for 45 minutes with 65% of maximum heart rate in the morning (7 - 8 am) and evening (5 - 6 pm) with a 2-day interval. Salivary immunoglobulin A, cortisol, and total protein levels were measured in the morning and evening (before and after the exercise) by ELISA method. Data were analyzed using analysis of variance with repeated measures and Bonferroni post hoc test. The results showed that morning exercise significantly decreased salivary cortisol concentration levels (P=0.03). No significant changes were observed in other measures. In conclusion, morning exercises reduces salivary cortisol levels in middle-aged men.

کلیدواژه‌ها [English]

  • circadian rhythm
  • immunoglobulin A
  • cortisol
  • total protein
  • middle-aged men
  1. Akimoto T, Akama T, Sugiura K. (1998). “Alteration of local immunity in the oral cavity after endurance running”. Japan Journal of Physical Fitness Sport Medicine, 47: 53-62.
  2. Allgrove JE, Geneen L, Latif S, Gleeson M. (2009). “Influence of a fed or fasted state on the s-IgA response to prolonged cycling in active men and women”. International Journal of Sport Nutrition Exercise and Metabolism, 19: 209-221.
  3. American College of Sports Medicine. (2006). “Guidelines for exercise testing and prescription”. Philadelphia: Lippincott, Williams and Wilkins, 14; PP: 532-48.
  4. Bird SP, & Tarpenning KM. (2004). “Influence of Circadian Time Structure on Acute Hormonal Responses to a Single Bout Men”. Publisher. Taylor and Francis, 21(1); PP: 131-146.
  5. Blannin AK, Robson PJ, Walsh NP, Clark AM, Glennon L, and Gleeson M. (1988). “The effect of exercising to exhaustion at different intensities on saliva immunoglobulin A, protein electrolyte secretion”. International Journal of Sports Medicine, 19:547-52.
  6. Deschenes Michael R, Kraemer William J, Bush Jill A, Doughty Todd A, Dorem Mullen K, Kathryn M, Kimberly R. (1998). “Biorhythmic Influences of Functional Capacity of Human Muscle and Physiological Responses”. Medicine and Science in Sports and Exercise, 30 (9):1399-1407.
  7. Dessypris A, Kuoppasalmi K, and Adlercreutz H. (2002). “Plasma Cortisol, Testosterone, Androstenedione and Luteinizing Hormone (LH) in a Non-Competitive Marathon Run (1976)”. Journal of Steroid Biochemistry, 7(1): 33-37.
  8. Dimitriou L, Sharp NCC, Doherty M. (2002). “Circadian effects on the acute responses of salivary cortisol and IgA in well trained swimmers”. British Journal of Sports Medicine, 36:260–264
  9. Fahlam MM, Engels HJ, Morgan Al, Kolokouri I. (2001). “Mucosal IgA Response to Repeated Wingate Tests in Females”. International Journal of Sports Medicine, 22: 127-131.

10.Fox PC. (2004). “Salivary enhancement therapies”. Caries Research, 38: 241-246.

11.Gleeson Mickael. (2006). “Immune Function in Sport and Exercise”. Churchili livingstone, Elsevier, The British Association of Sport and Exercise Sciences, PP:15-28.

12.Gleeson M, Lancaster GI, and Bishop NC. (2001). “Nutritional Strategies to Minimise Exercise Induced Immunosuppresion in Athletes”. Canadian Journal of Applied Physiology, 26: S23-S35.

13.Kerkhorf, G. A., Van Dongen, H. J. A. (1996). Morning-type and evening-type individuals differ in their phase position of their endogenous circadian oscillator. Neuroscience, Letters, 218:153–156.

14.Kiani M, Geramian Z, Saboori M, Shahed A. (2015). “Effect of different intensity aerobic activity on total protein concentration in saliva”. International Journal of Applied Exercise Physiology, 4(1): 12-22.

15.Luis-Penailillo L, Maya L, Nino N, Torres H & Zbinden-Foncea H. (2015). “Salivary hormones and IgA in relation to physical performance in football”. Journal of sports sciences, 12: 1-8.

16.Mackinnon LT. (1999). “Advances in exercise immunology”. 1st ed. Champaign (IL) Human Kinetics Pub, PP: 159-200.

17.Mandel ID. (1989). “The role of saliva in maintaining oral homeostasis”. Journal of American Dentist Association, 119:298-304.

18.Nieman DC, Henson DA, Dumke CL, Lind RH, and Shooter LR. (2006). “Relationship between salivary IgA secretion and upper respiratory tract infection following a 160-km race”. Journal of Sports Medicine Physical Fitness, 46:158-162.

19.Pederson BK & Koetz LH. (2002). “Exercise and Immune System: Regulation, Integration, and Adaptation Physiological Reviews”. Department of Infectious Diseases and Copenhagen Muscle Research Center, 80 (3):11-23.

20.Reilly T, Atkinson G, Waterhose W. (1997). “Biological Rhythms and Exercise”. Oxford Medical Publications, PP: 15-27.

21.Roschel H, Barroso R, Batista M, Ugrinowitsch C, Tricoli V, Arsati F, et al. (2011). “Do whole-body vibration exercise and resistance exercise modify concentrations of salivary cortisol and immunoglobulin A”? Brazilian Journal of Medical Biology Research, 44: 592-597.

22.Salminen S, Konttinen A. (1963). “Effect of exercise on Na and K concentration in human saliva and serum”. Journal of Apply Physiology, 18(4): 812-814.

23.Steerenberg PA, Van Asperen LA, Van Nieuw Amerongen A, Beiweng AJ, Medema GJ, and Mol D. (1997). “Salivary Levels of Immunoglobulin A in Triathletes”. European Journal of Oral Science, 105:305-309.

24.Tavakoly Z, Sari-Sarraf V, Amirsasan R. (2013). “Effect of time of day exercise on acute responses of salivary IgA, cortisol, α-amylase and total protein in female swimmers”. Journal of Metabolism, 2 (2):13-26.

25.Tzai-li li & Gleeson M. (2004). “The Effect of Single and Repeated Bouts of Prolonged Cycling and Circadian Variation on Saliva Flow Rate, Immunoglobulin A and - Amylase Responses”. Journal of sports Sciences, 22: 1015-1024.

26. van Eekelen, A. P. J., Kerkhof, G. A., van Amsterdam, J. G. (2003). Circadian variation in cortisol reactivity to an acute stressor. Chronobiology International, 20(5):863–878.

27.Walsh NP, Montague JC, Callow N, and Rowlands AV. (2004). “Saliva total protein concentration and osmolality as potential markers of hydration status during progressive acute dehydration in humans”. Arcadia, 49:149-154.

28.Zhao, Z. Y., Xie, Y., Fu, Y. R., Li, Y. Y., Bogdan, A., Touitou, Y. (2003). Circadian rhythm characteristics of serum cortisol and dehydroepiandrosterone sulfate in healthy Chinese men aged 30 to 60 years. A cross-sectional study. Steroids, 68:133–138.