تأثیر یک دوره تمرین استقامتی بر برخی شاخص‌های التهابی در مردان سیگاری

نوع مقاله: مقاله پژوهشی

نویسندگان

1 دانشجوی دکتری فیزیولوژی ورزشی قلب، عروق و تنفس، دانشگاه تهران، تهران، ایران

2 دانشیار گروه فیزیولوژی ورزش دانشگاه تهران، تهران، ایران

چکیده

 
افزایش سایتوکاین‌های ضدالتهابی و کاهش سایتوکاین‌های التهابی از طریق تمرین ورزشی یکی از روش­های کاهش التهاب مزمن است. پژوهش حاضر به‌منظور بررسی تأثیر تمرین استقامتی بر شاخص‌های التهابی در مردان سیگاری انجام گرفت. روش بررسی دو گروه، تجربی (میانگینسنی 95/2 ±30/25 سال،10n=) و گروه کنترل (میانگینسنی 76/2 ±11/26 سال ،10n=) به­صورت تصادفی انتخاب شدند. پروتکل تمرینی استقامتی شامل 20 دقیقه دویدن با شدت 55 تا 65 درصد ضربان قلب ذخیره، توسط گروه تجربی طی شش هفته اجرا شد. 48 ساعت پس از آخرین جلسۀ تمرینی اندازه‌گیری‌های مشابه پیش از تمرین و نمونۀ خون از آزمودنی­ها به­عمل آمد. ﺑﺮای تجزیه‌وتحلیل آﻣﺎری داده­ها در ﻫﺮ ﮔﺮوه از آزﻣﻮن t ﻫﻤﺒﺴﺘﻪ و ﺑﻴﻦ ﮔﺮوه­ها از آزﻣﻮن t ﻣﺴﺘﻘﻞ اﺳﺘﻔﺎده شد (05/0α).نتایج پژوهش حاضر نشان داد که 6 هفته مداخلۀ تمرین استقامتی موجب کاهش معنادار  CRP)012/ 0P=) و افزایش معنادار اینترلوکین-10 (01/ 0P=) در گروه تجربی شد. نتایج این پژوهش حاکی از تأثیر ورزش بر شاخص­های التهابی در مردان سیگاری است؛ از طرفی نشان می­دهد ممکن است افراد سیگاری با انجام فعالیت استقامتی بتوانند عوارض ناشی از مصرف سیگار را کاهش دهند. لیکن تأیید این مطلب نیازمند پژوهش‌های بیشتر در زمینۀ نقش تمرینات استقامتی و ارتباط آن با التهاب است.

کلیدواژه‌ها


عنوان مقاله [English]

The Effect of Endurance Training on Some Inflammatory Markers in Male Smokers

نویسندگان [English]

  • Hossein barzegari 1
  • SIROOS CHOOBINEH 2
  • ali akbarnejad 2
  • hafez rahimzadeh 1
1 PhD Student of Exercise Physiology of Cardiovascular and Respiratory, University of Tehran, Tehran, Iran
2 Associate Professor, Department of Exercise Physiology, University of Tehran, Tehran, Iran
چکیده [English]

 
Increased anti-inflammatory cytokines and decreased inflammatory cytokines through exercise is one of the ways to reduce chronic inflammation. Current study aimed at investigating the effect of endurance training on inflammatory markers in male smokers. Two groups: experimental (mean age 25.30 ± 2.95 years, n=10) and control (mean age 26.11 ± 2.76 years, n=10) were selected randomly. Endurance training protocol including of 20 minutes of running with intensity of 55-65% of heart rate reserve was performed by the experimental group during six weeks. 48 hours after the last training session, measurements similar to those before training and blood samples were collected. The data were analyzed by dependent t test within a group and independent t test between the groups (α≤0.05). The results showed that six weeks of endurance training intervention significantly decreased CRP (P=0.012) and significantly increased IL-10 (P=0.01) in the experimental group. The results indicated the effect of exercise on inflammatory markers in male smokers. On the other hand, these findings show that smokers may reduce the side effects of smoking if they have endurance training. But this requires further research on the role of endurance training and its relationship to inflammation.

کلیدواژه‌ها [English]

  • Inflammation
  • IL-10
  • Reactive Protein c
  • Endurance Training
  • Male Smokers
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