The Effect of Aerobic Exercise on Serum Levels of Adiponectin and CRP and Insulin Resistance in Women with Metabolic Syndrome

Document Type : Original Article

Authors

1 Associate Professor of Exercise Physiology, Faculty of Education and Psychology, Azarbaijan Shahid Madani University, Tabriz, Iran,

2 PhD Student of Exercise Physiology, Faculty of Physical Education and Sport Sciences, University of Guilan, Rasht, Iran

Abstract

 
Adiponectin is known as an adipokine with anti-inflammatory and anti- insulin resistance effects. The levels of this adipokine reduce in patients with metabolic syndrome. The aim of this study was to investigate the effect of aerobic exercise on serum levels of adiponectin and CRP and insulin resistance in women with metabolic syndrome. 24 women with metabolic syndrome (age: 55.14±4.28 yrs, weight: 93.44±9.29 kg and BMI: 32.65±1.51 kg/m2) were randomly divided into 2 groups: aerobic exercise (n=12) and control (n=12). Aerobic exercise subjects trained for 10 weeks, 3 sessions/week with an intensity of 60-70% of maximum heart rate reserve. Blood samples were collected at baseline and 48 hours after the last training session. ELISA was used to measure levels of serum variables and independent and dependent t tests were used for data analysis while the level of significance was considered P≤0.05. Data analysis showed that aerobic exercise significantly increased adiponectin and HDL, and significantly reduced CRP, glucose, insulin resistance, body weight, and waist circumference (P˂0.05). However, insulin, triglycerides and mean blood pressure changes were not significant after 10 weeks of aerobic exercise (P>0.05). Aerobic exercise is associated with an increase in serum adiponectin levels and the improvement of some metabolic syndrome markers and inflammatory states in women with metabolic syndrome and it seems that adiponectin changes can be a link between adipose tissue and the beneficial effects of aerobic exercise in women with metabolic syndrome.

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