تأثیر دو نوع شیوه مداخله (فعالیت هوازی و محدودیت کالریک) بر سطوح آیریزین سرم و شاخص مقاومت به انسولین در زنان چاق کم تحرک

نوع مقاله: مقاله پژوهشی

نویسندگان

1 دکترای فیزیولوژی ورزش، دانشکده تربیت بدنی و علوم ورزشی، دانشگاه تهران، ایران

2 دانشیار، گروه فیزیولوژی ورزشی، دانشکده تربیت بدنی، دانشگاه تهران، ایران

3 استاد دانشکده تربیت بدنی و علوم ورزشی، دانشگاه تهران، ایران

4 دانشیار،گروه فیزیولوژی ورزشی، دانشکده تربیت بدنی و علوم ورزشی دانشگاه تهران، تهران، ایران،

چکیده

هدف از پژوهش حاضر، بررسی تأثیر دو نوع مداخله فعالیت هوازی و رژیم کم کالری بر سطوح آیریزین سرم و شاخص مقاومت به انسولین در زنان چاق کم تحرک می باشد. به این منظور، ٣٠ نفر از زنان مراجعه کننده به خانه های سلامت شهرتهران (میانگین سنی ٢٨/٤±٣٣/٤١ سال؛ وزن٨٥/٦±4٣/٧٧ کیلوگرم)، به طور تصادفی درسه گروه فعالیت هوازی (تجربی 1)، رژیم کم کالری و فعالیت هوازی (تجربی2) و کنترل ( هر گروه 10 نفر) قرار گرفتند. برنامه تمرینی ١٦ هفته ای گروه تجربی 1 شامل 90 دقیقه فعالیت ائروبیک و دویدن بر روی تردمیل با میانگین مدت زمان٦٣/٥±١٨/١٥ دقیقه؛ هفته ای ٤ جلسه بود و در گروه تجربی 2 از رژیم غذایی با محدودیت کالریک و نیز فعالیت ورزشی معادل انرژی مصرفی گروه ١ استفاده گردید. میزان آیریزین سرم، گلوکز و انسولین و مقاومت به انسولین با روش ارزیابی مدل هموستاتیک (HOMA-IR)قبل و بعد از ١٦ هفته مداخله اندازه گیری گردید. کاهش معناداری در وزن، BMI،نسبت دور کمر به دور لگن (WHR)،آیریزین سرم، گلوکز ناشتا، انسولین ناشتا و HOMA-IRپس از کاهش وزن ناشی از فعالیت هوازی و محدودیت کالریکمشاهده گردید (05/0p<). بین تغییرات آیریزین سرم با تغییرات وزن، HOMA-IR و WHR همبستگی معناداری مشاهده گردید ((05/0p<).به نظر می رسد ١٦ هفته فعالیت ورزشی و رژیم کم کالری بر کاهش میزان آیریزین سرم، شاخص مقاومت به انسولین و ویژگیهای آنتروپومتریک در زنان چاق کم تحرک مؤثر باشد.

کلیدواژه‌ها


عنوان مقاله [English]

The Effect of Two Types of Intervention (Aerobic Exercise and Caloric Restriction) on Serum Irisin Levels and Insulin Resistance Index in Obese Sedentary Women

نویسندگان [English]

  • azam ramezankhani 1
  • rahman soori 2
  • ali asghar ravaasi 3
  • ali akbarnejad 4
1 PhD of Exercise Physiology, Faculty of Physical Education and Sport Sciences, University of Tehran, Tehran, Iran
2 Associate Professor, Faculty of Physical Education and Sport Sciences, University of Tehran, Tehran, Iran
3 Professor, Faculty of Physical Education and Sport Sciences, University of Tehran, Tehran, Iran
4 Associate Professor, Faculty of Physical Education and Sport Sciences, University of Tehran, Tehran, Iran
چکیده [English]

The aim of this study was to investigate the effect of two types of intervention (aerobic exercise and low calorie diet) on serum irisin levels and insulin resistance index in sedentary obese women. For this purpose, 30 women (mean±SD: age 41.33±4.28 yr; weight 77.43±6.85 kg) who referred to health centers in Tehran city were randomly assigned to three groups: aerobic exercise (experimental 1), low calorie diet and aerobic exercise (experimental 2) and control (each group 10 subjects). The program in experimental 1 group consisted of 90 minutes of aerobic exercise and running on a treadmill for 15.18±5.63 minutes, 4 sessions a week for 16 weeks. Experimental 2 group followed a diet with caloric restriction and physical activity equal to energy expenditure of experimental 1 group. Serum irisin, glucose, insulin and insulin resistance were measured using homeostatic model assessment (HOMA-IR) before and after 16 weeks of intervention. Weight, BMI, WHR, serum irisin, fasting glucose, fasting insulin and HOMA-IR decreased significantly after weight loss induced by aerobic exercise and caloric restriction (P<0.05). A significant correlation was observed between changes of serum irisin and changes of weight, WHR and HOMA-IR (P<0.05). It seems that 16 weeks of aerobic exercise and low caloric diet influenced the reduction of serum irisin, insulin resistance index and anthropometric profiles in sedentary obese women.

کلیدواژه‌ها [English]

  • Irisin
  • insulin resistance index
  • Aerobic exercise
  • low calorie diet
  • obese sedentary women

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