مقایسه تاثیر فعالیت هوازی بیشینه بر تغییرات آنتی اکسیدانی و ایمونوگلوبولین A بزاقی در مردان میانسال ورزشکار و غیر ورزشکار

نوع مقاله : مقاله پژوهشی


1 دانشجوی کارشناسی ارشد فیزیولوژی ورزشی ، دانشکده تربیت بدنی و علوم ورزشی، دانشگاه گیلان، رشت ، ایران

2 استاد فیزیولوژی ورزشی، دانشکده تربیت بدنی و علوم ورزشی، دانشگاه گیلان، رشت ، ایران

3 استاد بیوشیمی، دانشکده علوم، دانشگاه گیلان، رشت ، ایران


فعالیت‌های بدنی نقش مهمی در پیشگیری، به تأخیر انداختن و درمان مشکلات ناشی از فرآیند پیری و بهبود کیفیت زندگی دارند. هدف از این تحقیق، اندازه‌گیری شاخص‌های سیستم دفاع آنتی اکسیدانی و ایمونولوژیکی برای درک اثر فعالیت ورزشی هوازی بود. 12 ورزشکار مرد (سن 95/4±7/51 سال، وزن 51/4±5/67 کیلوگرم، شاخص توده بدن 92/0±93/23 کیلوگرم بر مترمربع) و 12 غیرورزشکار مرد (سن 28/3±91/52 سال، وزن 12/5±35/72 کیلوگرم، شاخص توده بدن 89/0±58/25 کیلوگرم بر مترمربع)، به صورت تصادفی هدفمند انتخاب شدند. آزمون تعدیل شده 20 متر شاتل ران برای فعالیت هوازی وامانده ساز مورد استفاده قرار گرفت. فعالیت آنزیم های سوپراکسیداز دیسموتاز(SOD) ، کاتالاز (CAT)، پراکسیداز (POD) و همچنین ایمونوگلوبولین A بزاقی قبل، بلافاصله بعد و یک ساعت بعد ازتمرین هوازی بیشینه اندازه گیری شد.بر اساس نتایج، فعالیت آنزیم‌های آنتی اکسیدانی در هر دو گروه بلافاصله بعد از فعالیت و هم چنین یک ساعت بعد از فعالیت، افزایش معناداری نسبت به قبل از فعالیت داشت. از طرفی، در هر دو گروه ورزشکار و غیر ورزشکار، تفاوت معنا دار بین مقدار ایمونوگلوبولین A قبل و بعد از تمرین ملاحظه نشد. در حالت ریکاوری نیز فعالیت آنزیم های CAT و SOD در گروه ورزشکار نسبت به غیر ورزشکار افزایش معناداری نشان دادند. به نظر می رسد که سابقه فعالیت ورزشی منظم در افراد ورزشکار می‌تواند باعث سازگاری بهینه و افزایش توان سیستم دفاعی آنتی اکسیدانی در مقابله با فشار اکسایشی گردد.


عنوان مقاله [English]

A Comparison of the Effect of Maximal Aerobic Exercise on Salivary Antioxidant and Immunoglobulin AChanges in Athlete and Non-Athlete Middle-Aged Men

نویسندگان [English]

  • Hamzeh Abdinejad 1
  • Arsallan Damirchi 2
  • Reihaneh Sariri 3
1 MSc student, Faculty of Physical Education and Exercise Science, University of Guilan, Rasht, Iran
2 Professor in Exercise Physiology, Faculty of Physical Education and Exercise Science, University of Guilan, Rasht, Iran
3 Professor in Biochemistry, Faculty of Sciences, University of Guilan, Rasht, Iran, Corresponding
چکیده [English]

Physical activity plays an important role in preventing, delayingand treating problems associated with aging and improving life quality. The aim of the present study was to measure the antioxidant and immunological defense system parameters in order to identify the effect of aerobic exercise. 12 male athletes (age 51.7±4.95 yr, weight 67.5±4.51 kg and BMI 23.93±0.92 kg/m2) and 12 non- athlete men (age 52.91±3.28yr, weight 72.35±5.12 kg and BMI 25.58±0.89kg/m2) were selected by random purposive sampling method. A modified 20m Shuttle Runexperiment was used for exhaustive physical activity. The activity of superoxide dismutase (SOD), catalase (CAT), peroxidase (POD) andsalivary immunoglobulin A wasmeasured before, immediately after and one hour after maximal aerobic exercise. The results showed that the activity of antioxidant enzymes significantly increased immediately after and also one hour after the exercise in both groupscompared with their value before the exercise. On the other hand, no significant differences were observed in the amount of immunoglobulin A before and after the exercise in both groups. During recovery, the activity of SOD and CAT enzymes showed a significant increase in the athlete group compared with the non-athlete group. It seems that a regular physical activity in athletes can induce efficient adaptation and increase antioxidant defense system power against oxidative stress.

کلیدواژه‌ها [English]

  • Aerobic exercise
  • Antioxidant enzymes
  • Saliva
  • immunoglobulinA
  • middle age
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